Research Paper Volume 11, Issue 23 pp 11591—11608

Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model

Figure 5. Representative WB, and quantification of neuroplasticity markers for SYN (A), PSD95 (B), and BDNF (C). Representative gene expression of neurotrophic factors for Ngf, and Vgf (D). Values in bar graphs are adjusted to 100% for protein levels of the Wt Control. Gene expression levels were determined by real-time PCR. Values represented are mean ± Standard error of the mean (SEM); (n = 4-6 for each group). *p<0.05; **p<0.01.