Research Paper Volume 11, Issue 23 pp 11591—11608

Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model

Figure 6. Representative images (A) and quantifications (B) of β-amyloid plaques stained with Thioflavin-S in Wt Control, 5XFAD Control and 5XFAD treated with UNC0642 (5mg/Kg). Values represented are mean ± Standard error of the mean (SEM); (n = 4 for each group). *p<0.05.