Figure 1. FHL3 referred to PDAC progression. (A and B) IHC staining and statistical analysis of FHL3 for sections from 55 matched different lesion stages tissues of PDAC and para-tumor normal area, which showed the higher expression level of FHL3 in PDAC, more than 3-fold, as compared with normal tissue, p<0.001. (C) Survival analysis via Kaplan-Meier analysis in 55 PDAC samples which showed higher expression level of FHL3 was accompanied with worse prognosis, p=0.0168. (D) WB assay of 8 matched fresh frozen PDAC samples, which showed higher expression level of FHL3 in PDAC tissues more than 1.5-fold, p<0.01.