Research Paper Volume 12, Issue 1 pp 53—69

FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors

Figure 7. Mechanism of FHL3 in regulation of EMT process. Protein which involved in signaling: AKT (AKT, ser437-AKT), GSK3β (GSK3β, ser9-GSK3β, try216-GSK3β), FHL3, snail1, twist1, TGFβ1, smad (smad2/3, smad4), and E-cadherin.