Research Paper Volume 11, Issue 24 pp 12375—12411

Discovering master regulators in hepatocellular carcinoma: one novel MR, SEC14L2 inhibits cancer cells


Figure 5. Profiling of conserved MRs. (A) Regulons are ranked by corresponding enrichment P-values, estimated for the HCC6, LIHC, and GSE14520 cohorts. (B) Network view of 44 consistent MRs. (C) GSEA of the top 10 MRs. (D) Examples of the top 10 MRs for which 2-tailed GSEA was carried out. (E) dES heatmap of the 44MRs.