Research Paper Volume 12, Issue 1 pp 70—79

MACC1-AS1 promotes hepatocellular carcinoma cell invasion and proliferation by regulating PAX8

Figure 6. PAX8 expression was upregulated in HCC tissues. (A) PAX8 expression was higher in HCC tissues than in nontumor tissues. (B) Compared to adjacent normal samples, 75% (30 of 40) of HCC samples showed overexpression of PAX8. (C) PAX8 was overexpressed in four HCC cell lines (QGY-7703, SMMC7721, MHCC-97H and HepG2) compared to the hepatocyte cell line (HL-7702). (D) PAX8 expression was positively correlated with MACC1-AS1 expression in HCC samples. ***p<0.001.