Research Paper Volume 12, Issue 1 pp 138—155

Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer

Figure 5. Anti-colorectal cancer activity of lycorine in xenograft mouse models. (A) Volume of the tumors after dissection. (B) Changes in tumor volume after treatment. (C) Changes in mouse weight after treatment. (D) Immunohistochemistry of the indicated proteins in vivo. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).