Research Paper Volume 12, Issue 1 pp 178—192

Genome-wide DNA copy number profiling and bioinformatics analysis of ovarian cancer reveals key genes and pathways associated with distinct invasive/migratory capabilities


Figure 2. Different biological behaviours and CNVs in OC cell lines. The migration distance in the HO-8910 cell line was less than that in the HO-8910PM cell line (p <0.01) (A). Cells were incubated on migration wells for 48 h, and the number of cells that migrated to the lower side of the filter was counted (B). The results are shown as the mean ± standard deviation (SD) (p <0.01 compared to the HO-8910 cell line). (C) Circos plot of the segmented CNVs in HO-8910PM (inner race) and HO-8910 (outer race) cell lines. Coloured bands expanding towards the centre or periphery of the diagram represent copy number losses or gains, respectively (red, gain; blue, loss).