Research Paper Volume 12, Issue 1 pp 178—192

Genome-wide DNA copy number profiling and bioinformatics analysis of ovarian cancer reveals key genes and pathways associated with distinct invasive/migratory capabilities

Figure 3. Functional enrichment analysis of “HO-8910PM-specific gain” and “HO-8910PM-specific loss” genes identified in CNV regions. (A) GO-based annotation was used for the functional enrichment analysis of genes with shared “HO-8910PM-specific gains” (479 genes). (B) KEGG pathway analysis of genes with shared “HO-8910PM-specific gains” (479 genes). (C) GO-based annotation was used for the functional enrichment analysis of genes with shared “HO-8910PM-specific loss” (400 genes) through DAVID. (D) KEGG pathway analysis of genes with shared “HO-8910PM-specific loss” (400 genes). Colour represents the -log of the P value for the significance of enrichment. Only annotations with significant P values < 0.05 are shown.