Figure 5. Effects of IL-12p35 KO on mitochondrial dysfunction. (A, B). Cardiac 8-OHdg expression (200x) and mitochondrial 8-OHdg levels were detected. (C). The activity of mitochondrial enzyme complexes I, II, III and IV in the four groups was measured. (D). The mitochondrial ATP levels in each group were detected. * p<0.05 vs. the young WT group; # p<0.05 vs. the aged WT group; n=4-5 for each group.