Research Paper Volume 11, Issue 24 pp 12810—12821

Nicotine instigates podocyte injury via NLRP3 inflammasomes activation

Figure 7. Effect of NAC (N-acetyl-cysteine), ROS scavenger on nicotine-induced inflammasome activation. Values are arithmetic means ± SEM (n=6 each group) of caspase-1 activity (A) and IL-β production (B) in podocytes with or without stimulation of nicotine and/or NAC. *significant difference from control, # significant difference from nicotine treated group.