Research Paper Volume 11, Issue 24 pp 12810—12821

Nicotine instigates podocyte injury via NLRP3 inflammasomes activation

Figure 8. ROS scavenger N-acetyl-cysteine (NAC) protected podocyte from nicotine-induced podocyte injury. Representative immunofluorescence images and summarized quantification data (n=6 each group) shows podocin (A) and nephrin (B) expression in podocytes treated with or without stimulation of nicotine and/or NAC. Images were quantified using Image J software. *significant difference from control, #significant difference from nicotine treated group.