Figure 1. The rotation test and open field test for rats in each group (n = 12). (A) The number of rotation circles in each group of PD model rats induced by apomorphine; (B) The total distance moved of rats in each group; (C) The average movement speed of rats in each group; (D) The duration of movement in the central grid in one minute of rats in each group; (E) The results of the stepping test; (F) The results of the cylinder test; * P < 0.05 vs the normal group; # P < 0.05 vs the mimics NC group; & P < 0.05 vs the miR-375 mimics group. The measurement data were expressed as mean ± standard deviation and ANOVA was used for the comparison among multiple groups. After ANOVA analysis, the Tukey’s post-hoc test was used for pairwise comparison.