Research Paper Volume 12, Issue 1 pp 784—807

CCL14 is a prognostic biomarker and correlates with immune infiltrates in hepatocellular carcinoma

Figure 4. Correlation analysis of CCL14 expression and the expression of marker genes of infiltrating immune cells in HCC (A-G) and CHOL (H-N) using the TIMER database. (AG) The scatter plots show correlation between CCL14 expression and the gene markers of (A) Monocytes (CD86); (B) Neutrophils (ITGAM and CCR7); (C) TAMs (IL-10 and CD68); (D) Th1 cells (TBX21, TNF, IFNG and STAT1); (E) Th2 cells (STAT6); (F) Tregs (CCR8, STAT5B and TGFB1); and (G) Exhausted T cells (HAVCR2, PDCD1 and CTLA4) in HCC samples (n = 371). (HN) The scatter plots show correlations between CCL14 expression and the gene markers of (H) Monocytes (CD86); (I) Neutrophils (ITGAM and CCR7); (J) TAMs (IL-10 and CD68); (K)Th1 cells (TBX21, TNF, IFNG and STAT1); (L) Th2 cells (STAT6); (M) Tregs (CCR8, STAT5B and TGFB1); and (N) Exhausted T cells (HAVCR2, PDCD1 and CTLA4) in CHOL (n = 36).