Research Paper Volume 12, Issue 1 pp 965—977

Prediction of hepatocellular carcinoma prognosis based on expression of an immune-related gene set

Figure 4. IPSHCC typing and sensitivity analysis. (A) Immune scores are calculated based on IPSHCC coefficients in antimicrobial, cytokine, and cytokine receptor immune processes. Scores were divided between low and high immune risk groups based on the median value. Median survival times were compared using the log-rank test. (B, C) To test the robustness of IPSHCC, we randomly re-sampled 500 cases from the consolidated datasets 10,000 times. (B) Histogram showing –log10 (P) values from the 10,000 resampled datasets. P-values were < 0.05 for all samples. (C) Histogram of C-index values from the 10,000 resampled datasets. The median C-index value was 0.6819, and standard deviation (SD) was 0.0091, demonstrating robust predictive ability.