Research Paper Volume 12, Issue 6 pp 4711—4726

Silencing of lncRNA XIST inhibits non-small cell lung cancer growth and promotes chemosensitivity to cisplatin

Figure 6. Induction of pyroptosis by DDP in NSCLC cells and facilitatory role of XIST. (A) Analysis of apoptosis by annexin V/PI staining and flow cytometry in NSCLC cells. (B) Western blot detection of apoptosis-related proteins. (C) Morphological changes in si-XIST-transfected, DDP-treated NSCLC cells. (D, E) Western blot analysis of pyroptosis-related proteins. * < 0.05 vs si-nc group, # < 0.05 vs DDP + si-nc group.