Research Paper Volume 12, Issue 3 pp 2049—2069

Targeting of miR-96-5p by catalpol ameliorates oxidative stress and hepatic steatosis in LDLr-/- mice via p66shc/cytochrome C cascade

Figure 1. Catalpol ameliorated hepatic steatosis in LDLr-/- mice. The mice were fed with normal or western diet for 16-week, and then sacrificed for morphological and pathological observation. (A) Representative morphological images of liver sections. (B) H&E- stained sections of liver sections. H&E-stained sections were photographed at 200× magnification. (C) Transmission electron microscopy of liver sections. The liver sections were photographed at 10 000× magnification. The lipid droplets were indicated by arrows. ND: normal diet; WD: western diet.