Research Paper Volume 12, Issue 3 pp 2049—2069

Targeting of miR-96-5p by catalpol ameliorates oxidative stress and hepatic steatosis in LDLr-/- mice via p66shc/cytochrome C cascade

Figure 3. Catalpol inhibited oxidative stress, promoted ATP production and inhibited hepatic apoptosis. (A) SOD level. (B) MDA level. (C) CAT level. (D) ATP content. (E) ATPase activity. (F) 8-OHdG level. The results are the mean± SD (n=10), **P< 0.05 vs. Control group, ##P < 0.05 vs. WD group. (G) Tunel staining for hepatic apoptosis. Tunel stained sections were photographed at 200× magnification. ND: normal diet; WD: western diet.