Research Paper Volume 12, Issue 3 pp 2070—2083

Mitochondria and aging in older individuals: an analysis of DNA methylation age metrics, leukocyte telomere length, and mitochondrial DNA copy number in the VA normative aging study


Figure 1. Cross-sectional associations of Mitochondrial DNA Copy Number (mtDNAcn) with DNA Methylation Age (DNAm-Age), DNAm-PhenoAge, DNAm-GrimAge, and Telomere Length. The effect estimates (β) and corresponding 95% confidence intervals were estimated with linear mixed models adjusted for chronological age, smoking, alcohol use, BMI, hypertension status, CHD status, diabetes status, blood cell type composition, and follow up time.