Inhibition of <i>miR-193a-3p</i> protects human umbilical vein endothelial cells against intermittent hypoxia-induced endothelial injury by targeting FAIM2

Qingshi Chen; Guofu Lin; Jianchai Huang; Lida Chen; Yibin Liu; Jiefeng Huang; Shuyi Zhang; Qichang Lin

doi:doi:10.18632/aging.102729

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Research Paper Volume 12, Issue 2 pp 1899—1909

Inhibition of miR-193a-3p protects human umbilical vein endothelial cells against intermittent hypoxia-induced endothelial injury by targeting FAIM2

Figure 3. miR-193a-3p silence alleviates IH-induced injury in HUVECs. Cells were transfected with miR-193a-3p inhibitor, and negative control. Cells with normoxia treatment were acted as control. (A) Cell viability. (B, C) Expression levels of apoptosis-related proteins. β-Actin was served as internal control. IH: intermittent hypoxia; n = 3. (Data are presented as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001).