Research Paper Volume 12, Issue 3 pp 2261—2274

TYRO3 facilitates cell growth and metastasis via activation of the Wnt/β-catenin signaling pathway in human gastric cancer cells


Figure 4. The effects of TYRO3 knockdown or overexpression on the epithelial-mesenchymal transition and Wnt/β-catenin signaling-related markers in gastric cancer (GC) cells. Following TYRO3 shRNA or overexpression treatment, (A) qRT-PCR, (B) western blotting, and (C) immunofluorescence detection of the indicated expression levels (TYRO3, β-catenin, c-myc, cyclinD1, survivin, E-cadherin, Slug, and N-cadherin) in modified GC cells. Glyceraldehyde 3-phosphate dehydrogenase was used as a loading control. *P < 0.05.