Research Paper Volume 12, Issue 3 pp 2347—2372

Protein disulfide isomerases are promising targets for predicting the survival and tumor progression in glioma patients


Figure 6. (A, B) The risk score model of PDI family in gliomas was established on the basis of LASSO coefficients. The distributions of clinical features and PDIs expression according to the risk scores from low to high in TCGA and CGGA are displayed by heat maps. (C–J) The risk scores differences between subgroups classified by subtype, MGMT promoter status, 1p19q codel status, IDH status, gender, age, grade, and cancer in LGGGBM cohort. TCGA database as training set and CGGA database as the validation set. *** p < 0·001, NS. p > 0·05.