Research Paper Volume 12, Issue 3 pp 2453—2470

The whole transcriptome regulation as a function of mitochondrial polymorphisms and aging in Caenorhabditis elegans

Figure 1. Both mitochondrial and nuclear genomes correlate with the quantitative traits of development and lifespan of Caenorhabditis elegans. (A) Average lifespans in strains N2, CB4856, N2-mitotype RIAILs, CB4856-mitotype RIAILs and CN30. (B) Lifespan of 34 N2-CB4856 recombinant inbred advanced intercross lines (RIAILs). (C) Motility of 0, 6, 9 and 12-day-old worms (darker color in the heatmap indicates weaker motility). (D) Histogram of normalized body length in control (gray) and in paraquat (black) conditions for 210 RIAILs. Statistical analysis was performed by using two-tailed unequal variant Student’s t-test (* P-value < 0.05, ** P-value < 0.01).