Research Paper Volume 12, Issue 3 pp 2471—2484

Sepsis induced cognitive impairments by disrupting hippocampal parvalbumin interneuron-mediated inhibitory network via a D4-receptor mechanism


Figure 2. Altered hippocampal PV expression and LFP after CLP. (AB) PV expression decreased significantly at 14 days after CLP compared with sham group (n = 4). (CD) Decreased PV expression was observed in all subregions of the hippocampus 14 days after CLP (n = 4). (EF) Slow γ oscillation band was significantly decreased in CLP group when compared with sham group, but there was no difference in θ, α, β, or fast γ band power between these two groups (n = 3). Data are shown as mean ± SD, *P < 0.05 vs sham group, scale bar = 50 μm.