Figure 5. Interactions of gene-drug and potential biological roles of some genes. (A) Pie distributions of associations of 26 genes and pathways, and their roles in pathways, activation or inhibition, are also presented. (B) Gene-drug interactions in CCA. All of these involved drugs are predicted with positive (DR > 0.1, p < 0.05) or negative (DR < -0.1, p < 0.05) correlations. Red lines show significant positive or negative correlation. (C) Survival analysis of TPX2 in relevant cancer types showing their potential role in disease prognosis.