Research Paper Volume 12, Issue 3 pp 2764—2776

Age-specific differential changes on gut microbiota composition in patients with major depressive disorder

Figure 2. 16S rRNA gene sequencing reveals changes to microbial abundances in young MDD patients. (A) OPLS-DA model showed an obvious difference in microbial abundances between the two groups (HCs, n=27; MDD, (n=25); (B) the relative abundances of Firmicutes and Bacteroidetes were significantly changed in young MDD patients (n=25) as compared with young HCs (n=27).