Research Paper Volume 12, Issue 4 pp 3140—3155

Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer

Figure 2. LP/P germline BRCA1/2 mutations detected in this cohort. (A) 11 LP/P mutations found in BRCA1. (B) 18 LP/P mutations found in BRCA2. Colored boxes depict the different functional domains along the gene. Small colored circles denote the type of mutation while the location of the circle specifies the mutation site. A patient is represented by a circle. The length of the lollipop represents the number of people of a specific variant.