Research Paper Volume 12, Issue 3 pp 2897—2920

Identifying lncRNA–miRNA–mRNA networks to investigate Alzheimer’s disease pathogenesis and therapy strategy

Figure 7. Identified lncRNA-associated ceRNA networks in APP/PS1 mice. The ceRNA networks were constructed based on identified lncRNA–miRNA and miRNA–mRNA interactions. The networks include decreased lncRNAs, increased miRNAs, and decreased mRNAs in APP/PS1 mice. (A) 6yes9no group, and (B) 6no9yes group.