Research Paper Volume 12, Issue 3 pp 2921—2938

The nuclear localization signal-mediated nuclear targeting of herpes simplex virus 1 early protein UL2 is important for efficient viral production

Figure 2. The predicted NLS2 of UL2 is nonfunctional. (A) Schematic representation of WT UL2 and its deletion mutants UL2(1-75), UL2(69-224), UL2(61-224), UL2(69-75) and UL2(61-75) fused with EYFP. (B) Subcellular localization of these UL2 deletion mutants (shown in A) in plasmid-transfected live COS-7 cells. All scale bars indicate 10 μm.