Research Paper Volume 12, Issue 4 pp 3175—3189

Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice

Figure 2. Ligustilide improves aging-induced cognitive dysfunction in SAMP8 mice. (A) Trajectory map for each respective group in the new object recognition. (B) Times by each respective group exploring a reference object and a new object. (C) Trajectory map for each respective group in the field test. (D) Time spent by each respective group in the field test. (E) Trajectory map for each respective group in the elevated plus maze. (F) Time spent by each respective group in the elevated plus maze. Ligustilide 10 (10 mg/kg/d); Ligustilide 20 (20 mg/kg/d). Data represent mean ± SD (n = 20 per group). #p < 0.05, ##p < 0.01, ###p < 0.001 versus SAMR1; *p < 0.05, **p < 0.01, ***p < 0.001 versus SAMP8.