Research Paper Volume 12, Issue 4 pp 3218—3237

LINC00623/miR-101/HRAS axis modulates IL-1β-mediated ECM degradation, apoptosis and senescence of osteoarthritis chondrocytes

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Figure 7. The expression of IL-1β and the correlation of LINC00623, miR-101, HRAS and IL-1β in tissue samples. (AC) The correlation of LINC00623, miR-101 and HRAS expression was analyzed using Spearman’s rank correlation analysis. (D) The mRNA expression of IL-1β in normal and OA tissues were detected using real-time PCR. The data are presented as mean ± SD of three independent experiments. **P<0.01. (EG) The correlation of IL-1β with LINC00623, miR-101 and HRAS expression, respectively, was analyzed using Spearman’s rank correlation analysis.