Research Paper Volume 12, Issue 4 pp 3354—3370

Cancer stem cell-specific expression profiles reveal emerging bladder cancer biomarkers and identify circRNA_103809 as an important regulator in bladder cancer

Figure 7. circRNA_103809 induces bladder cancer progression by sponging miR-511. (A) qRT-PCR analysis of the transfection efficiency of siRNA transfection in EJ cells. Under-expression of circRNA_103809 causes a diminished oncosphere (B), migration (C) and invasion (D) capacity in EJ cells. (E) qRT-PCR analysis of miR-130, miR329, miR511, miR532 and miR-642 expression in EJ cells. (F) EJ cell lysates were subject to RNA pull-down assay. miR-511 can be pulled down by circRNA_103809 probe.