Research Paper Volume 12, Issue 4 pp 3451—3472

Existence of intratumoral tertiary lymphoid structures is associated with immune cells infiltration and predicts better prognosis in early-stage hepatocellular carcinoma

Figure 4. Subgroup analysis based on clinicopathologic features (early RFS). TLS was significantly correlated with early tumor relapse in patients with BCLC 0-A stage HCC other than those with advanced tumors. TLS, tertiary lymphoid structures; AFP, alpha-fetoprotein; BCLC, Barcelona Clinic of Liver Cancer; TNM, tumor-nodes-metastasis.