Figure 3. ENSG00000254041.1 promotes cell cycle and cell proliferation in PC cells. (A) Knockdown of the ENSG00000254041.1 expression decreased the percentage of S-phase and increased G0/G1 phase cell in both of SW1990 and BxPC-3 cells, while overexpression of ENSG00000254041.1 in Panc-1 cells resulted in the opposite effects. (B) Downregulation of ENSG00000254041.1 inhibited proliferation of SW1990 and BxPC-3, while overexpression of ENSG00000254041.1 promoted Panc-1 cells proliferation. Three samples in each group. *p < 0.05, **p < 0.01, ***p < 0.001 compared with si-NC or vector.