Figure 6. ENSG00000254041.1 increase the chemoresistance of PC cells to gemcitabine in vitro. (A) GSEA analysis revealed that ENSG00000254041.1 expression associated with the multi-drug resistance. (B) Knockdown of ENSG00000254041.1 decreased the IC50 values of GEM in SW1990 and BxPC-3 cells, and overexpression of ENSG00000254041.1 in Panc-1 cells increased the IC50 values of GEM. ***p < 0.001 compared with indicated group.