Editorial Volume 12, Issue 3 pp 2024—2025

Targeting aged bone marrow for systemic rejuvenation

Figure 1. Systemic rejuvenation using young bone marrow. Schematic diagram showing that following reconstitution of old bone marrow with young cells the transplanted cells can repopulate peripheral organs such as the heart, lung, brain, and skeletal muscle. Young bone marrow cells interact with host cells to influence cellular function and act to improve tissue responses to injury.