Research Paper Volume 12, Issue 5 pp 4163—4177

Reduced Ca2+ spark activity contributes to detrusor overactivity of rats with partial bladder outlet obstruction

Figure 1. Decreased STOC frequency and amplitude in detrusor myocytes of DO rats. (A) Representative traces of STOCs in detrusor myocytes from control and DO rats. (B) Traces at a -40 mV holding potential from detrusor myocytes of control and DO rats. (C) Summarized data for measures of STOC frequency and amplitude. At all voltages, the frequencies (a) and amplitudes (b) of STOCs in DO rats were significantly lower than respective measures for rats in control groups. We used unpaired t tests for comparisons between groups. VS control *P<0.05, **P<0.01.