Research Paper Volume 12, Issue 5 pp 4163—4177

Reduced Ca2+ spark activity contributes to detrusor overactivity of rats with partial bladder outlet obstruction

Figure 3. Unaltered SR Ca2+ load in detrusor myocytes of DO model rats. (A) Representative linescan images during 10 mM caffeine application in control (a) and DO (b) myocytes. (B) Peak amplitude of the caffeine-evoked fluorescence [Ca2+] i transient was not found to have been significantly different between DO afflicted and unafflicted control myocytes. We used unpaired t tests for comparisons between treatment groups. NS=Not significant.