Research Paper Volume 12, Issue 5 pp 4163—4177

Reduced Ca2+ spark activity contributes to detrusor overactivity of rats with partial bladder outlet obstruction

Figure 7. Decreased expression of ryanodine receptor-2 (RyR2) and increased expression of FKBP12.6 in detrusors of rats with DO. (A) Representative results from Western blotting analyses of RyR2, FKBP12.6, and GADPH (used as an internal control) from detrusors of unafflicted control rats and from DO afflicted rats. (B) Summarizations of levels of expression of RyR2 and FKBP12.6 proteins, given as ratios to beta actin. We used one-way ANOVA for comparisons between treatment groups. VS control, *P < 0.05, and **P < 0.01.