Figure 3. Efficient antibiotic treatment and transplant. Antibiotic treatment reduces (A) Chao1 diversity and (B) bacterial copy number. (C) Principal Coordinate Analysis of mice and donor gut microbiomes based on unweighted UniFrac distance. Triangles represent the L group and circles represent the E group. Different colors represent different time periods. (D) The Chao1 diversity of E group and L group after transplantation. ***p <0.001, ****p<0.0001, Mann-Whitney U test.