Figure 1. Characteristics of rats. Whole body weights of each group of rats during the 20-week experimental period (A). Whole body weights (B), epidydimal and post peritoneal fat weights (C), lower limb muscle weights (D), kidney weights (E) and kidney weights per g body weight (BW) (F) at the end of the study (n=7). The data shown are the means ± SD. ##p<0.01, ### p<0.001 vs. diabetes, *p<0.05, **p<0.01, ***p<0.001 vs. the indicated groups. ns: not significant. White circles: control, black circles: diabetes, white triangles: diabetes + LPD, black triangles: diabetes + LPD + Met. LPD: low-protein diet, Met: methionine, BW: body weight.