Research Paper Volume 12, Issue 5 pp 4489—4505

Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetes

Figure 6. Morphology of mitochondria in PTCs and autophagy. Representative TEM images of PTCs (scale bar: 500 nm) (A). Asterisks indicate elongated (>2 μm) mitochondria (A). The ratio of PTCs without elongation of mitochondria to total PTCs (B) (from 3 animals). Representative western blots of p62 and β-actin expression (C) and the quantitative ratios of p62 to β-actin in the renal cortex (D) (n=7). The data shown are the means ± SD. **p<0.01, ***p<0.001 vs. the indicated groups. ns: not significant. PTCs: proximal tubular cells, TEM: transmission electron microscopy.