Research Paper Volume 12, Issue 6 pp 4836—4865

Nrf2 deficiency aggravates PM2.5-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder

Figure 5. Nrf2 loss promotes autophagy initiation in PM2.5-challenged mice. (A) Representative images of western blotting bands for Beclin1, Vps34, LC3B and ATG5 in cardiac tissues. (B) Relative quantification of these molecules by western blot analysis. n = 6 in each group. Data were expressed as the mean ± SEM. *P < 0.05.