Research Paper Volume 12, Issue 6 pp 4836—4865

Nrf2 deficiency aggravates PM2.5-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder

Figure 6. Nrf2 knockout enhances abnormal glucose metabolism in hearts of PM2.5-exposed mice. (A) GCK, (B) PK and (C) SDH activities in hearts of mice were measured. n = 7 or 8 in each group. (D) RT-qPCR was used to measure GCK, PK, HK1, G6Pase and PERCK mRNA levles in hearts of mice. n = 6 in each group. Data were expressed as the mean ± SEM. *P < 0.05; ns, no significant difference.