Research Paper Volume 12, Issue 5 pp 4527—4546

LncRNA-LALR1 upregulates small nucleolar RNA SNORD72 to promote growth and invasion of hepatocellular carcinoma

Figure 3. Knock-down of lncRNA-LALR1 inhibits growth of HCC cells in vivo. (A) The tumor volumes after knockdown of lncRNA-LALR1. (B) Knockdown of lncRNA-LALR1 decreases tumor volumes. (C) Knockdown of lncRNA-LALR1 decreases tumor weights. (D) Immunohistochemistry showing lncRNA-LALR1 silencing leads to a reduce of Ki67 protein levels. (E) LncRNA-LALR1 silencing reduces Ki67 protein levels. *: P < 0.05; **: P < 0.01; ***: P < 0.001.