Research Paper Volume 12, Issue 6 pp 4879—4895

A nine-gene signature related to tumor microenvironment predicts overall survival with ovarian cancer

Figure 2. Differentially expressed genes based on immune scores and stromal scores. (A) The volcano plot showed that 438 genes were up-regulated and 42 genes down-regulated in the high immune scores group compared with the low scores group. (B) In a similar way, 414 upregulated genes and 18 downregulated genes were identified by comparing stromal scores. (C, D) Significantly enriched gene sets of the immune or stromal score group. (E, F) A total of 281 DEGs were in common among the high immune/stromal score groups and 13 DEGs in low immune/stromal score groups.