Research Paper Volume 12, Issue 5 pp 4641—4659

Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson’s disease models

Figure 8. Immunostaining of TH in dopaminergic neurons. Transverse section taken through the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA), immunostained for TH to evaluate the dopaminergic-induced injury by stereotaxic injection of 6-OHDA in the right side. Histograms shows the percentage of TH+ fibers loss in striatum (CPu) and TH+ cell bodies in substantia nigra (SN) (expressed in percentage of unlesioned side). * p< 0.05, *** p< 0.0005 vs Ctr; + p< 0.05, ++ p< 0.005 vs 6-OHDA.