Research Paper Volume 12, Issue 6 pp 5259—5279

Whole-transcriptome analysis reveals a potential hsa_circ_0001955/hsa_circ_0000977-mediated miRNA-mRNA regulatory sub-network in colorectal cancer

Figure 11. Validation of hsa_circ_0001955-mediated miRNA-mRNA sub-network in CRC using clinical tissue samples. Expression of hsa_circ_0001955 (A), hsa-miR-145-5p (B), CDK4 (C), MMP12 (D) and RAB3IP (E) in CRC cancer samples compared with normal samples. Expression correlation between hsa_circ_0001955/hsa-miR-145-5p (F), hsa-miR-145-5p/CDK4 (G), hsa-miR-145-5p/MMP12 (H), hsa-miR-145-5p/RAB3IP (I), hsa_circ_0001955/CDK4 (J), hsa_circ_0001955/MMP12 (K) and hsa_circ_0001955/RAB3IP (L) pairs in CRC. *p<0.05 represents significant difference.