**Figure 4.** **Identification of potential miRNAs that bind to circRNAs in colorectal cancer.** (**A**) The volcano plot of differentially expressed miRNAs (DEmiRNAs) in colorectal cancer from GSE126093 dataset. The red dots and green dots represent upregulated DEmiRNAs and downregulated DEmiRNAs with significance (adjusted P-value < 0.05 and |log_{2}FC| > 1), respectively. The black dots are those DEmiRNAs without significance. (**B**) The intersection analysis of target miRNAs of upregulated circRNAs and downregulated DEmiRNA. (**C**) The intersection analysis of target miRNAs of downregulated circRNAs and upregulated DEmiRNA. (**D**) The expression level of hsa-miR-145-5p in COAD. (**E**) The expression level of hsa-miR-3127-5p in COAD. (**F**) The expression level of hsa-miR-761 in COAD. (**G**) The expression level of hsa-miR-4766-3p in COAD. (**H**) The expression level of hsa-miR-135a-5p in COAD. (**I**) The expression level of hsa-miR-135b-5p in COAD. (**J**) The expression level of hsa-miR-374a-3p in COAD. (**K**) The expression level of hsa-miR-330-3p in COAD. “p<0.05” represents significant difference and “ns” represents no significance.