Research Paper Volume 12, Issue 6 pp 5439—5468

Identification of hub genes in hepatocellular carcinoma using integrated bioinformatic analysis

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Figure 7. MCM3 and SPATS2 promotes HCC cell proliferation. (AB) Proliferation of HCC cells with MCM3 or SPATS2 knockdown according to CCK-8 analysis. (CD) EdU assays showing the proportion of S-phase cell after downregulating the expression of MCM3 or SPATS2. Nuclei of S-phase cells were pink. (EH) Statistical analysis of EdU incorporation. *P < 0.05; **P < 0.01; ***P < 0.001.