Research Paper Volume 12, Issue 6 pp 5439—5468

Identification of hub genes in hepatocellular carcinoma using integrated bioinformatic analysis

Figure 7. MCM3 and SPATS2 promotes HCC cell proliferation. (AB) Proliferation of HCC cells with MCM3 or SPATS2 knockdown according to CCK-8 analysis. (CD) EdU assays showing the proportion of S-phase cell after downregulating the expression of MCM3 or SPATS2. Nuclei of S-phase cells were pink. (EH) Statistical analysis of EdU incorporation. *P < 0.05; **P < 0.01; ***P < 0.001.